Cargando…

Cancer-Associated Fibroblasts and Tumor Cells in Pancreatic Cancer Microenvironment and Metastasis: Paracrine Regulators, Reciprocation and Exosomes

SIMPLE SUMMARY: Cancer-associated fibroblasts in the stromal tumor microenvironment play a key role in cancer progression, invasion, metastasis, and therapy resistance. Cancer-associated fibroblasts communicate with tumor cells through diverse factors, such as growth factors, hedgehog proteins, cyto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sunami, Yoshiaki, Häußler, Johanna, Zourelidis, Anais, Kleeff, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833704/ https://www.ncbi.nlm.nih.gov/pubmed/35159011 http://dx.doi.org/10.3390/cancers14030744

Ejemplares similares

Cellular Heterogeneity of Pancreatic Stellate Cells, Mesenchymal Stem Cells, and Cancer-Associated Fibroblasts in Pancreatic Cancer
por: Sunami, Yoshiaki, et al.
Publicado: (2020)

Targeting and Reprograming Cancer-Associated Fibroblasts and the Tumor Microenvironment in Pancreatic Cancer
por: Sunami, Yoshiaki, et al.
Publicado: (2021)

Cholesterol Metabolism in Pancreatic Cancer
por: Rebelo, Artur, et al.
Publicado: (2023)

Single Cell Analysis of Cultivated Fibroblasts from Chronic Pancreatitis and Pancreatic Cancer Patients
por: Sunami, Yoshiaki, et al.
Publicado: (2022)

Lipid Metabolism and Lipid Droplets in Pancreatic Cancer and Stellate Cells
por: Sunami, Yoshiaki, et al.
Publicado: (2017)

Analysis of genomic alterations in cancer associated human pancreatic stellate cells
por: Böker, Viktoria, et al.
Publicado: (2022)

Identification of prognostic lipid droplet-associated genes in pancreatic cancer patients via bioinformatics analysis
por: Bai, Rubing, et al.
Publicado: (2021)

Fibroblast Activation Protein Overexpression in Gastrointestinal Tumors: Protocol for a Systematic Review and Meta-analysis
por: Sunami, Yoshiaki, et al.
Publicado: (2023)

Lipid Droplet-Associated Factors, PNPLA3, TM6SF2, and HSD17B Proteins in Hepatopancreatobiliary Cancer
por: Sunami, Yoshiaki, et al.
Publicado: (2021)

A Role of Tumor-Released Exosomes in Paracrine Dissemination and Metastasis
por: Spugnini, Enrico Pierluigi, et al.
Publicado: (2018)

Reciprocal Interactions between Fibroblast and Pancreatic Neuroendocrine Tumor Cells: Putative Impact of the Tumor Microenvironment
por: Cuny, Thomas, et al.
Publicado: (2022)

Reciprocal Regulation of Cancer-Associated Fibroblasts and Tumor Microenvironment in Gastrointestinal Cancer: Implications for Cancer Dormancy
por: Cheng, Shih-Hsuan, et al.
Publicado: (2023)

The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors
por: Bolm, Louisa, et al.
Publicado: (2017)

Paracrine and cell autonomous signalling in pancreatic cancer progression and metastasis
por: Thomas, Stacy K., et al.
Publicado: (2020)

Crosstalk between Pancreatic Cancer Cells and Cancer-Associated Fibroblasts in the Tumor Microenvironment Mediated by Exosomal MicroRNAs
por: Chu, Xiangyu, et al.
Publicado: (2022)

Cancer-associated fibroblasts contribute to oral cancer cells proliferation and metastasis via exosome-mediated paracrine miR-34a-5p
por: Li, Yao-yin, et al.
Publicado: (2018)

Cancer-Associated Fibroblasts Influence the Biological Properties of Malignant Tumours via Paracrine Secretion and Exosome Production
por: Vokurka, Martin, et al.
Publicado: (2022)

Tumor microenvironment participates in metastasis of pancreatic cancer
por: Ren, Bo, et al.
Publicado: (2018)

Brain derived neutrophic factor (BDNF) coordinates lympho-vascular metastasis through a fibroblast-governed paracrine axis in the tumor microenvironment
por: Jiffar, Tilahun, et al.
Publicado: (2017)

Heterogeneity of Cancer-Associated Fibroblasts and the Tumor Immune Microenvironment in Pancreatic Cancer
por: Shinkawa, Tomohiko, et al.
Publicado: (2022)

Aberrant low expression of p85α in stromal fibroblasts promotes breast cancer cell metastasis through exosome-mediated paracrine Wnt10b
por: Chen, Y, et al.
Publicado: (2017)

Paracrine activin B-NF-κB signaling shapes an inflammatory tumor microenvironment in gastric cancer via fibroblast reprogramming
por: Jin, Yangbing, et al.
Publicado: (2023)

Perspective: bidirectional exosomal transport between cancer stem cells and their fibroblast-rich microenvironment during metastasis formation
por: Valcz, Gábor, et al.
Publicado: (2018)

Exosomal tetraspanins mediate cancer metastasis by altering host microenvironment
por: Lu, Jun, et al.
Publicado: (2017)

STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer
por: Lefler, Julia E, et al.
Publicado: (2022)

Cancer-associated fibroblasts and its derived exosomes: a new perspective for reshaping the tumor microenvironment
por: Peng, Zhiwei, et al.
Publicado: (2023)

Apoptosis in the Pancreatic Cancer Tumor Microenvironment—The Double-Edged Sword of Cancer-Associated Fibroblasts
por: Pfeifer, Ester, et al.
Publicado: (2021)

Intestinal autotransplantation: the next level of complexity in locally advanced pancreatic cancer
por: Rebelo, Artur, et al.
Publicado: (2023)

Crosstalk between colorectal cancer cells and cancer-associated fibroblasts in the tumor microenvironment mediated by exosomal noncoding RNAs
por: Sun, Shichen, et al.
Publicado: (2023)

The potential roles of exosomes in pancreatic cancer initiation and metastasis
por: Sun, Wei, et al.
Publicado: (2020)

Cancer genome and tumor microenvironment: Reciprocal crosstalk shapes lung cancer plasticity
por: Mansouri, Siavash, et al.
Publicado: (2022)

The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance
por: Asare-Werehene, Meshach, et al.
Publicado: (2019)

CANCER-ASSOCIATED FIBROBLAST EXOSOMES REGULATE SURVIVAL AND PROLIFERATION OF PANCREATIC CANCER CELLS
por: Richards, Katherine E., et al.
Publicado: (2016)

Pancreatic cancer and fibrosis: Targeting metabolic reprogramming and crosstalk of cancer-associated fibroblasts in the tumor microenvironment
por: Li, Xin, et al.
Publicado: (2023)

Surgery for synchronous and metachronous single-organ metastasis of pancreatic cancer: a SEER database analysis and systematic literature review
por: Liu, Qiaofei, et al.
Publicado: (2020)

Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis
por: Murata, Takuya, et al.
Publicado: (2017)

Exosomal MicroRNAs Mediating Crosstalk Between Cancer Cells With Cancer-Associated Fibroblasts and Tumor-Associated Macrophages in the Tumor Microenvironment
por: Su, Tong, et al.
Publicado: (2021)

Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts
por: Li, Qing, et al.
Publicado: (2019)

Exosomes in the tumor microenvironment: Promoting cancer progression
por: Jin, Ye, et al.
Publicado: (2022)

Crosstalk and plasticity driving between cancer-associated fibroblasts and tumor microenvironment: significance of breast cancer metastasis
por: Zhang, Wenfeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s34lhssptjjnurrutl7invbrr6