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Exact Primary Tumor Location in mCRC: Prognostic Value and Predictive Impact on Anti-EGFR mAb Efficacy

SIMPLE SUMMARY: Sidedness of primary tumor is a well-established prognostic marker and is predictive for anti-EGFR efficacy in RAS/BRAF wild-type metastatic colorectal cancer (mCRC) patients. As molecular markers change rather continuously throughout the colon, we ask whether the exact primary tumor...

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Detalles Bibliográficos
Autores principales: Alig, Annabel H. S., Heinemann, Volker, Geissler, Michael, Fischer von Weikersthal, Ludwig, Decker, Thomas, Heinrich, Kathrin, Held, Swantje, Weiss, Lena, Fischer, Laura E., Moosmann, Nicolas, Stahler, Arndt, Jelas, Ivan, Kurreck, Annika, von Einem, Jobst C., Reinacher-Schick, Anke C., Tannapfel, Andrea, Giessen-Jung, Clemens, Stintzing, Sebastian, Modest, Dominik P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833757/
https://www.ncbi.nlm.nih.gov/pubmed/35158793
http://dx.doi.org/10.3390/cancers14030526