Sphingosine Kinase-1 Is Overexpressed and Correlates with Hypoxia in Osteosarcoma: Relationship with Clinicopathological Parameters

SIMPLE SUMMARY: Hypoxia has been recognized as a hallmark of solid tumors and a negative prognostic factor for response to therapeutics and survival of patients. Studies have demonstrated that the Sphingosine kinase-1/Sphingosine 1-Phosphate (SphK1/S1P) signaling pathway regulates the expression of...

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Detalles Bibliográficos
Autores principales: Gomez-Brouchet, Anne, Illac, Claire, Ledoux, Adeline, Fortin, Pierre-Yves, de Barros, Sandra, Vabre, Clémentine, Despas, Fabien, Peries, Sophie, Casaroli, Christelle, Bouvier, Corinne, Aubert, Sébastien, de Pinieux, Gonzague, Larousserie, Frédérique, Galmiche, Louise, Talmont, Franck, Pitson, Stuart, Maddelein, Marie-Lise, Cuvillier, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833796/
https://www.ncbi.nlm.nih.gov/pubmed/35158767
http://dx.doi.org/10.3390/cancers14030499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833796/
https://www.ncbi.nlm.nih.gov/pubmed/35158767
http://dx.doi.org/10.3390/cancers14030499

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