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Hydrogen Sulfide Upregulates Acid-sensing Ion Channels via the MAPK-Erk1/2 Signaling Pathway

Hydrogen sulfide (H(2)S) emerged recently as a new gasotransmitter and was shown to exert cellular effects by interacting with proteins, among them many ion channels. Acid-sensing ion channels (ASICs) are neuronal voltage-insensitive Na(+) channels activated by extracellular protons. ASICs are invol...

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Detalles Bibliográficos
Autores principales: Peng, Zhong, Kellenberger, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833866/
https://www.ncbi.nlm.nih.gov/pubmed/35330812
http://dx.doi.org/10.1093/function/zqab007