Cargando…

Notch Signaling in HSC Emergence: When, Why and How

The hematopoietic stem cell (HSC) sustains blood homeostasis throughout life in vertebrates. During embryonic development, HSCs emerge from the aorta-gonads and mesonephros (AGM) region along with hematopoietic progenitors within hematopoietic clusters which are found in the dorsal aorta, the main a...

Descripción completa

Detalles Bibliográficos
Autores principales: Thambyrajah, Roshana, Bigas, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833884/
https://www.ncbi.nlm.nih.gov/pubmed/35159166
http://dx.doi.org/10.3390/cells11030358