Impact of Organelle Transport Deficits on Mitophagy and Autophagy in Niemann–Pick Disease Type C

Defective mitochondria are pathophysiological features of a number of neurodegenerative diseases. Here, we investigated mitochondrial dysfunction in the context of the rare lysosomal storage diseases Niemann–Pick disease type C1 and type C2 (NP-C1 and NP-C2). Mutations in either the NPC1 or NPC2 gen...

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Detalles Bibliográficos
Autores principales: Liedtke, Maik, Völkner, Christin, Hermann, Andreas, Frech, Moritz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833886/
https://www.ncbi.nlm.nih.gov/pubmed/35159316
http://dx.doi.org/10.3390/cells11030507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833886/
https://www.ncbi.nlm.nih.gov/pubmed/35159316
http://dx.doi.org/10.3390/cells11030507

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