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Interferon-γ Preferentially Promotes Necroptosis of Lung Epithelial Cells by Upregulating MLKL

Necroptosis, a form of programmed lytic cell death, has emerged as a driving factor in the pathogenesis of acute lung injury (ALI). As ALI is often associated with a cytokine storm, we determined whether pro-inflammatory cytokines modulate the susceptibility of lung cells to necroptosis and which me...

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Detalles Bibliográficos
Autores principales: Hao, Qin, Shetty, Sreerama, Tucker, Torry A., Idell, Steven, Tang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833897/
https://www.ncbi.nlm.nih.gov/pubmed/35159372
http://dx.doi.org/10.3390/cells11030563