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Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging

A plethora of factors have been attributed to underly aging, including oxidative stress, telomere shortening and cellular senescence. Several studies have shown a significant role of the cyclin-dependent kinase inhibitor p16ink4a in senescence and aging. However, its expression in development has be...

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Detalles Bibliográficos
Autores principales: Safwan-Zaiter, Hasan, Wagner, Nicole, Michiels, Jean-François, Wagner, Kay-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833900/
https://www.ncbi.nlm.nih.gov/pubmed/35159350
http://dx.doi.org/10.3390/cells11030541