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The Role of the Lysosomal Cl(−)/H(+) Antiporter ClC-7 in Osteopetrosis and Neurodegeneration
CLC proteins comprise Cl(−) channels and anion/H(+) antiporters involved in several fundamental physiological processes. ClC-7 is a lysosomal Cl(−)/H(+) antiporter that together with its beta subunit Ostm1 has a critical role in the ionic homeostasis of lysosomes and of the osteoclasts’ resorption l...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833911/ https://www.ncbi.nlm.nih.gov/pubmed/35159175 http://dx.doi.org/10.3390/cells11030366 |