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Collagen Biomarkers Quantify Fibroblast Activity In Vitro and Predict Survival in Patients with Pancreatic Ductal Adenocarcinoma

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease. New tools which can aid in the understanding of PDAC biology and novel drug development are needed. We established an in vitro fibroblast model in combination with collagen biomarkers as a translational anti-fibrotic d...

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Detalles Bibliográficos
Autores principales: Nissen, Neel I., Johansen, Astrid Z., Chen, Inna, Johansen, Julia S., Pedersen, Rasmus S., Hansen, Carsten P., Karsdal, Morten A., Willumsen, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833921/
https://www.ncbi.nlm.nih.gov/pubmed/35159087
http://dx.doi.org/10.3390/cancers14030819