Lactate Activates Germline and Cleavage Embryo Genes in Mouse Embryonic Stem Cells

Lactate was recently found to mediate histone lysine lactylation and facilitate polarization of M1 macrophages, indicating its role in metabolic regulation of gene expression. During somatic cell reprogramming, lactate promotes histone lactylation of pluripotency genes and improves reprogramming eff...

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Detalles Bibliográficos
Autores principales: Tian, Qing, Zhou, Li-quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833948/
https://www.ncbi.nlm.nih.gov/pubmed/35159357
http://dx.doi.org/10.3390/cells11030548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833948/
https://www.ncbi.nlm.nih.gov/pubmed/35159357
http://dx.doi.org/10.3390/cells11030548

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