Inosine Triphosphate Pyrophosphatase (ITPase): Functions, Mutations, Polymorphisms and Its Impact on Cancer Therapies

Inosine triphosphate pyrophosphatase (ITPase) is an enzyme encoded by the ITPA gene and functions to prevent the incorporation of noncanonical purine nucleotides into DNA and RNA. Specifically, the ITPase catalyzed the hydrolysis of (deoxy) nucleoside triphosphates ((d) NTPs) into the corresponding...

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Detalles Bibliográficos
Autor principal: Zamzami, Mazin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833965/
https://www.ncbi.nlm.nih.gov/pubmed/35159194
http://dx.doi.org/10.3390/cells11030384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833965/
https://www.ncbi.nlm.nih.gov/pubmed/35159194
http://dx.doi.org/10.3390/cells11030384

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