Limited Metabolic Effect of the CREBRF(R457Q) Obesity Variant in Mice

The Arg457Gln missense variant in the CREBRF gene has previously been identified as driving excess body weight in Pacific/Oceanic populations. Intriguingly, Arg457Gln variant carriers also demonstrate paradoxical reductions in diabetes risk, indicating that the gene has a critical role in whole-body...

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Detalles Bibliográficos
Autores principales: Metcalfe, Louise K., Shepherd, Peter R., Smith, Greg C., Turner, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833978/
https://www.ncbi.nlm.nih.gov/pubmed/35159305
http://dx.doi.org/10.3390/cells11030497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833978/
https://www.ncbi.nlm.nih.gov/pubmed/35159305
http://dx.doi.org/10.3390/cells11030497

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