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Aged Mouse Hippocampus Exhibits Signs of Chronic Hypoxia and an Impaired HIF-Controlled Response to Acute Hypoxic Exposures

Altered hypoxia-inducible factor-alpha (HIF-α) activity may have significant consequences in the hippocampus, which mediates declarative memory, has limited vascularization, and is vulnerable to hypoxic insults. Previous studies have reported that neurovascular coupling is reduced in aged brains and...

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Detalles Bibliográficos
Autores principales: Snyder, Brina, Wu, Hua-Kang, Tillman, Brianna, Floyd, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833982/
https://www.ncbi.nlm.nih.gov/pubmed/35159233
http://dx.doi.org/10.3390/cells11030423