Highlighting the Multifaceted Role of Orai1 N-Terminal- and Loop Regions for Proper CRAC Channel Functions

Orai1, the Ca(2+)-selective pore in the plasma membrane, is one of the key components of the Ca(2+)release-activated Ca(2+) (CRAC) channel complex. Activated by the Ca(2+) sensor in the endoplasmic reticulum (ER) membrane, stromal interaction molecule 1 (STIM1), via direct interaction when ER lumina...

Descripción completa

Detalles Bibliográficos
Autores principales: Humer, Christina, Romanin, Christoph, Höglinger, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834118/
https://www.ncbi.nlm.nih.gov/pubmed/35159181
http://dx.doi.org/10.3390/cells11030371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834118/
https://www.ncbi.nlm.nih.gov/pubmed/35159181
http://dx.doi.org/10.3390/cells11030371

Ejemplares similares