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Highlighting the Multifaceted Role of Orai1 N-Terminal- and Loop Regions for Proper CRAC Channel Functions
Orai1, the Ca(2+)-selective pore in the plasma membrane, is one of the key components of the Ca(2+)release-activated Ca(2+) (CRAC) channel complex. Activated by the Ca(2+) sensor in the endoplasmic reticulum (ER) membrane, stromal interaction molecule 1 (STIM1), via direct interaction when ER lumina...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834118/ https://www.ncbi.nlm.nih.gov/pubmed/35159181 http://dx.doi.org/10.3390/cells11030371 |