S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent

Alterations of methionine cycle in steatohepatitis, cirrhosis, and hepatocellular carcinoma induce MAT1A decrease and MAT2A increase expressions with the consequent decrease of S-adenosyl-L-methionine (SAM). This causes non-alcoholic fatty liver disease (NAFLD). SAM administration antagonizes pathol...

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Detalles Bibliográficos
Autores principales: Pascale, Rosa M., Simile, Maria M., Calvisi, Diego F., Feo, Claudio F., Feo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834208/
https://www.ncbi.nlm.nih.gov/pubmed/35159219
http://dx.doi.org/10.3390/cells11030409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834208/
https://www.ncbi.nlm.nih.gov/pubmed/35159219
http://dx.doi.org/10.3390/cells11030409

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