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Plasma Small Extracellular Vesicles with Complement Alterations in GRN/C9orf72 and Sporadic Frontotemporal Lobar Degeneration

Cutting-edge research suggests endosomal/immune dysregulation in GRN/C9orf72-associated frontotemporal lobar degeneration (FTLD). In this retrospective study, we investigated plasma small extracellular vesicles (sEVs) and complement proteins in 172 subjects (40 Sporadic FTLD, 40 Intermediate/Patholo...

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Detalles Bibliográficos
Autores principales: Bellini, Sonia, Saraceno, Claudia, Benussi, Luisa, Squitti, Rosanna, Cimini, Sara, Ricci, Martina, Canafoglia, Laura, Coppola, Cinzia, Puoti, Gianfranco, Ferrari, Clarissa, Longobardi, Antonio, Nicsanu, Roland, Lombardi, Marta, D’Arrigo, Giulia, Verderio, Claudia, Binetti, Giuliano, Rossi, Giacomina, Ghidoni, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834212/
https://www.ncbi.nlm.nih.gov/pubmed/35159297
http://dx.doi.org/10.3390/cells11030488