Characterization of Gfat1 (zeppelin) and Gfat2, Essential Paralogous Genes Which Encode the Enzymes That Catalyze the Rate-Limiting Step in the Hexosamine Biosynthetic Pathway in Drosophila melanogaster

The zeppelin (zep) locus is known for its essential role in the development of the embryonic cuticle of Drosophila melanogaster. We show here that zep encodes Gfat1 (Glutamine: Fructose-6-Phosphate Aminotransferase 1; CG12449), the enzyme that catalyzes the rate-limiting step in the hexosamine biosy...

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Detalles Bibliográficos
Autores principales: Cotsworth, Shawn, Jackson, Catherine J., Hallson, Graham, Fitzpatrick, Kathleen A., Syrzycka, Monika, Coulthard, Alistair B., Bejsovec, Amy, Marchetti, Marcella, Pimpinelli, Sergio, Wang, Simon J. H., Camfield, Robert G., Verheyen, Esther M., Sinclair, Donald A., Honda, Barry M., Hilliker, Arthur J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834284/
https://www.ncbi.nlm.nih.gov/pubmed/35159258
http://dx.doi.org/10.3390/cells11030448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834284/
https://www.ncbi.nlm.nih.gov/pubmed/35159258
http://dx.doi.org/10.3390/cells11030448

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