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Characterization of Gfat1 (zeppelin) and Gfat2, Essential Paralogous Genes Which Encode the Enzymes That Catalyze the Rate-Limiting Step in the Hexosamine Biosynthetic Pathway in Drosophila melanogaster
The zeppelin (zep) locus is known for its essential role in the development of the embryonic cuticle of Drosophila melanogaster. We show here that zep encodes Gfat1 (Glutamine: Fructose-6-Phosphate Aminotransferase 1; CG12449), the enzyme that catalyzes the rate-limiting step in the hexosamine biosy...
Autores principales: | Cotsworth, Shawn, Jackson, Catherine J., Hallson, Graham, Fitzpatrick, Kathleen A., Syrzycka, Monika, Coulthard, Alistair B., Bejsovec, Amy, Marchetti, Marcella, Pimpinelli, Sergio, Wang, Simon J. H., Camfield, Robert G., Verheyen, Esther M., Sinclair, Donald A., Honda, Barry M., Hilliker, Arthur J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834284/ https://www.ncbi.nlm.nih.gov/pubmed/35159258 http://dx.doi.org/10.3390/cells11030448 |
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