Targeting Mitochondrial COX-2 Enhances Chemosensitivity via Drp1-Dependent Remodeling of Mitochondrial Dynamics in Hepatocellular Carcinoma

SIMPLE SUMMARY: New therapeutic strategies are urgently needed to improve the anti-cancer effect for hepatocellular carcinoma (HCC). Overexpression of cyclooxygenase-2 (COX-2) is found in several types of cancers and correlates with a poor prognosis. However, it remains unclear how the mitochondrial...

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Detalles Bibliográficos
Autores principales: Che, Lin, Wu, Jia-Shen, Du, Ze-Bang, He, Yu-Qiao, Yang, Lei, Lin, Jin-Xian, Lei, Zhao, Chen, Xiao-Xuan, Guo, Dong-Bei, Li, Wen-Gang, Lin, Yu-Chun, Lin, Zhong-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834292/
https://www.ncbi.nlm.nih.gov/pubmed/35159089
http://dx.doi.org/10.3390/cancers14030821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834292/
https://www.ncbi.nlm.nih.gov/pubmed/35159089
http://dx.doi.org/10.3390/cancers14030821

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