Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells

Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Of the four molecular subgroups, Group 3 MB is the most aggressive and has the worst prognosis. To understand the origins of chemoresistance involving IL-6/STAT3 signaling, we used in vitro co-culture systems to investigate the...

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Detalles Bibliográficos
Autores principales: Sreenivasan, Lakshana, Li, Ling Vicky, Leclair, Pascal, Lim, Chinten James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834329/
https://www.ncbi.nlm.nih.gov/pubmed/35159191
http://dx.doi.org/10.3390/cells11030381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834329/
https://www.ncbi.nlm.nih.gov/pubmed/35159191
http://dx.doi.org/10.3390/cells11030381

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