Evidence of Adult Features and Functions of Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells and Self-Organized as Organoids

Background: Human-induced pluripotent stem cell-derived hepatocytes (iHeps) have been shown to have considerable potential in liver diseases, toxicity, and pharmacological studies. However, there is a growing need to obtain iHeps that are truly similar to primary adult hepatocytes in terms of morpho...

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Detalles Bibliográficos
Autores principales: Messina, Antonietta, Luce, Eléanor, Benzoubir, Nassima, Pasqua, Mattia, Pereira, Ulysse, Humbert, Lydie, Eguether, Thibaut, Rainteau, Dominique, Duclos-Vallée, Jean-Charles, Legallais, Cécile, Dubart-Kupperschmitt, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834365/
https://www.ncbi.nlm.nih.gov/pubmed/35159346
http://dx.doi.org/10.3390/cells11030537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834365/
https://www.ncbi.nlm.nih.gov/pubmed/35159346
http://dx.doi.org/10.3390/cells11030537

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