Cargando…

Zscan4 Contributes to Telomere Maintenance in Telomerase-Deficient Late Generation Mouse ESCs and Human ALT Cancer Cells

Proper telomere length is essential for indefinite self-renewal of embryonic stem (ES) cells and cancer cells. Telomerase-deficient late generation mouse ES cells and human ALT cancer cells are able to propagate for numerous passages, suggesting telomerase-independent mechanisms responding for telom...

Descripción completa

Detalles Bibliográficos
Autores principales: Dan, Jiameng, Zhou, Zhongcheng, Wang, Fang, Wang, Hua, Guo, Renpeng, Keefe, David L., Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834411/
https://www.ncbi.nlm.nih.gov/pubmed/35159266
http://dx.doi.org/10.3390/cells11030456