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Zscan4 Contributes to Telomere Maintenance in Telomerase-Deficient Late Generation Mouse ESCs and Human ALT Cancer Cells
Proper telomere length is essential for indefinite self-renewal of embryonic stem (ES) cells and cancer cells. Telomerase-deficient late generation mouse ES cells and human ALT cancer cells are able to propagate for numerous passages, suggesting telomerase-independent mechanisms responding for telom...
Autores principales: | Dan, Jiameng, Zhou, Zhongcheng, Wang, Fang, Wang, Hua, Guo, Renpeng, Keefe, David L., Liu, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834411/ https://www.ncbi.nlm.nih.gov/pubmed/35159266 http://dx.doi.org/10.3390/cells11030456 |
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