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Optimization of Thymidine Kinase-Based Safety Switch for Neural Cell Therapy

Cell therapies based on pluripotent stem cells (PSC), have opened new therapeutic strategies for neurodegenerative diseases. However, insufficiently differentiated PSC can lead to tumor formation. Ideally, safety switch therapies should selectively kill proliferative transplant cells while preservin...

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Detalles Bibliográficos
Autores principales: Locatelli, Manon, Delhaes, Flavien, Cherpin, Ophélie, Black, Margaret E., Carnesecchi, Stéphanie, Preynat-Seauve, Olivier, Hibaoui, Youssef, Krause, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834506/
https://www.ncbi.nlm.nih.gov/pubmed/35159311
http://dx.doi.org/10.3390/cells11030502