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Optimization of Thymidine Kinase-Based Safety Switch for Neural Cell Therapy
Cell therapies based on pluripotent stem cells (PSC), have opened new therapeutic strategies for neurodegenerative diseases. However, insufficiently differentiated PSC can lead to tumor formation. Ideally, safety switch therapies should selectively kill proliferative transplant cells while preservin...
Autores principales: | Locatelli, Manon, Delhaes, Flavien, Cherpin, Ophélie, Black, Margaret E., Carnesecchi, Stéphanie, Preynat-Seauve, Olivier, Hibaoui, Youssef, Krause, Karl-Heinz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834506/ https://www.ncbi.nlm.nih.gov/pubmed/35159311 http://dx.doi.org/10.3390/cells11030502 |
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