Epiregulin as an Alternative Ligand for Leptin Receptor Alleviates Glucose Intolerance without Change in Obesity

The leptin receptor (LepR) acts as a signaling nexus for the regulation of glucose uptake and obesity, among other metabolic responses. The functional role of LepR under leptin-deficient conditions remains unclear. This study reports that epiregulin (EREG) governed glucose uptake in vitro and in viv...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, No-Joon, Lee, Aejin, Yasmeen, Rumana, Shen, Qiwen, Yang, Kefeng, Kumar, Shashi Bhushan, Muhanna, Danah, Arnipalli, Shanvanth, Noria, Sabrena F., Needleman, Bradley J., Hazey, Jeffrey W., Mikami, Dean J., Ortega-Anaya, Joana, Jiménez-Flores, Rafael, Prokop, Jeremy, Ziouzenkova, Ouliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834548/
https://www.ncbi.nlm.nih.gov/pubmed/35159237
http://dx.doi.org/10.3390/cells11030425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834548/
https://www.ncbi.nlm.nih.gov/pubmed/35159237
http://dx.doi.org/10.3390/cells11030425

Ejemplares similares