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Epiregulin as an Alternative Ligand for Leptin Receptor Alleviates Glucose Intolerance without Change in Obesity

The leptin receptor (LepR) acts as a signaling nexus for the regulation of glucose uptake and obesity, among other metabolic responses. The functional role of LepR under leptin-deficient conditions remains unclear. This study reports that epiregulin (EREG) governed glucose uptake in vitro and in viv...

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Detalles Bibliográficos
Autores principales:	Song, No-Joon, Lee, Aejin, Yasmeen, Rumana, Shen, Qiwen, Yang, Kefeng, Kumar, Shashi Bhushan, Muhanna, Danah, Arnipalli, Shanvanth, Noria, Sabrena F., Needleman, Bradley J., Hazey, Jeffrey W., Mikami, Dean J., Ortega-Anaya, Joana, Jiménez-Flores, Rafael, Prokop, Jeremy, Ziouzenkova, Ouliana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834548/ https://www.ncbi.nlm.nih.gov/pubmed/35159237 http://dx.doi.org/10.3390/cells11030425

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