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The GABA Polarity Shift and Bumetanide Treatment: Making Sense Requires Unbiased and Undogmatic Analysis
GABA depolarizes and often excites immature neurons in all animal species and brain structures investigated due to a developmentally regulated reduction in intracellular chloride concentration ([Cl(−)](i)) levels. The control of [Cl(−)](i) levels is mediated by the chloride cotransporters NKCC1 and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834580/ https://www.ncbi.nlm.nih.gov/pubmed/35159205 http://dx.doi.org/10.3390/cells11030396 |