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Defective Cystinosin, Aberrant Autophagy−Endolysosome Pathways, and Storage Disease: Towards Assembling the Puzzle

Epithelial cells that form the kidney proximal tubule (PT) rely on an intertwined ecosystem of vesicular membrane trafficking pathways to ensure the reabsorption of essential nutrients—a key requisite for homeostasis. The endolysosome stands at the crossroads of this sophisticated network, internali...

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Detalles Bibliográficos
Autores principales: Rega, Laura Rita, De Leo, Ester, Nieri, Daniela, Luciani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834619/
https://www.ncbi.nlm.nih.gov/pubmed/35159136
http://dx.doi.org/10.3390/cells11030326