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Deletion of Specific Conserved Motifs from the N-Terminal Domain of αB-Crystallin Results in the Activation of Chaperone Functions

Smaller oligomeric chaperones of α-crystallins (αA- and αB-) have received increasing attention due to their improved therapeutic potential in preventing protein aggregating diseases. Our previous study suggested that deleting 54–61 residues from the N-terminal domain (NTD) of αB-crystallin (αBΔ54–6...

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Detalles Bibliográficos
Autores principales:	Mahalingam, Sundararajan, Shankar, Goutham, Mooney, Brian P., Singh, Kamal, Santhoshkumar, Puttur, Sharma, Krishna K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834691/ https://www.ncbi.nlm.nih.gov/pubmed/35163023 http://dx.doi.org/10.3390/ijms23031099

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