Apoptosis as Driver of Therapy-Induced Cancer Repopulation and Acquired Cell-Resistance (CRAC): A Simple In Vitro Model of Phoenix Rising in Prostate Cancer

Apoptotic cells stimulate compensatory proliferation through the caspase-3-cPLA-2-COX-2-PGE-2-STAT3 Phoenix Rising pathway as a healing process in normal tissues. Phoenix Rising is however usurped in cancer, potentially nullifying pro-apoptotic therapies. Cytotoxic therapies also promote cancer cell...

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Detalles Bibliográficos
Autores principales: Corsi, Francesca, Capradossi, Francesco, Pelliccia, Andrea, Briganti, Stefania, Bruni, Emanuele, Traversa, Enrico, Torino, Francesco, Reichle, Albrecht, Ghibelli, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834753/
https://www.ncbi.nlm.nih.gov/pubmed/35163077
http://dx.doi.org/10.3390/ijms23031152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834753/
https://www.ncbi.nlm.nih.gov/pubmed/35163077
http://dx.doi.org/10.3390/ijms23031152

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