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Role of Organic Cation Transporter 2 in Autophagy Induced by Platinum Derivatives

The human organic cation transporter 2 (hOCT2) mediates renal and neuronal cellular cisplatin and oxaliplatin uptake, and therefore plays a significant role in the development of side effects associated with these chemotherapeutic drugs. Autophagy is induced by cisplatin and oxaliplatin treatment an...

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Detalles Bibliográficos
Autores principales: Eltayeb, Sara Ahmed, Ciarimboli, Giuliano, Beul, Katrin, Seno Di Marco, Giovana, Barz, Vivien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834759/
https://www.ncbi.nlm.nih.gov/pubmed/35163014
http://dx.doi.org/10.3390/ijms23031090