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Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer’s, and Parkinson’s Diseases

Iron accumulates in the ageing brain and in brains with neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and Down syndrome (DS) dementia. However, the mechanisms of iron deposition and regional selectivity in the brain are ill-understo...

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Detalles Bibliográficos
Autores principales: Raha, Animesh Alexander, Biswas, Anwesha, Henderson, James, Chakraborty, Subhojit, Holland, Anthony, Friedland, Robert P., Mukaetova-Ladinska, Elizabeta, Zaman, Shahid, Raha-Chowdhury, Ruma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834792/
https://www.ncbi.nlm.nih.gov/pubmed/35162984
http://dx.doi.org/10.3390/ijms23031060