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Utilization of CRISPR-Mediated Tools for Studying Functional Genomics in Hematological Malignancies: An Overview on the Current Perspectives, Challenges, and Clinical Implications

Hematological malignancies (HM) are a group of neoplastic diseases that are usually heterogenous in nature due to the complex underlying genetic aberrations in which collaborating mutations enable cells to evade checkpoints that normally safeguard it against DNA damage and other disruptions of healt...

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Detalles Bibliográficos
Autores principales: Solayappan, Maheswaran, Azlan, Adam, Khor, Kang Zi, Yik, Mot Yee, Khan, Matiullah, Yusoff, Narazah Mohd, Moses, Emmanuel Jairaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834884/
https://www.ncbi.nlm.nih.gov/pubmed/35154242
http://dx.doi.org/10.3389/fgene.2021.767298