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In Vivo Rapid Investigation of CRISPR-Based Base Editing Components in Escherichia coli (IRI-CCE): A Platform for Evaluating Base Editing Tools and Their Components

Rapid assessment of clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas)-based genome editing (GE) tools and their components is a critical aspect for successful GE applications in different organisms. In many bacteria, double-strand breaks (DSBs) generate...

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Detalles Bibliográficos
Autores principales: Shelake, Rahul Mahadev, Pramanik, Dibyajyoti, Kim, Jae-Yean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834901/
https://www.ncbi.nlm.nih.gov/pubmed/35163069
http://dx.doi.org/10.3390/ijms23031145