Beneficial and Sexually Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder. There is no cure and current treatments fail to slow the progression of the disease. Epigenetic modulation in the acetylation state of NF-kB RelA and the histone 3 (H3) protein, involved in the development of neur...

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Detalles Bibliográficos
Autores principales: Bankole, Oluwamolakun, Scambi, Ilaria, Parrella, Edoardo, Muccilli, Matilde, Bonafede, Roberta, Turano, Ermanna, Pizzi, Marina, Mariotti, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835218/
https://www.ncbi.nlm.nih.gov/pubmed/35162978
http://dx.doi.org/10.3390/ijms23031047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835218/
https://www.ncbi.nlm.nih.gov/pubmed/35162978
http://dx.doi.org/10.3390/ijms23031047

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