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Changes of Gut Microbiota by Natural mtDNA Variant Differences Augment Susceptibility to Metabolic Disease and Ageing

We recently reported on two mouse strains carrying different single nucleotide variations in the mitochondrial complex I gene, i.e., B6-mt(BPL) mice carrying m.11902T>C and B6-mt(ALR) carrying m.4738C>A. B6-mt(BPL) mice exhibited a longer lifespan and a lower metabolic disease susceptibility d...

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Detalles Bibliográficos
Autores principales: Künstner, Axel, Schilf, Paul, Busch, Hauke, Ibrahim, Saleh M., Hirose, Misa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835372/
https://www.ncbi.nlm.nih.gov/pubmed/35162979
http://dx.doi.org/10.3390/ijms23031056