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The Promoter of the Immune-Modulating Gene TIR-Containing Protein C of the Uropathogenic Escherichia coli Strain CFT073 Reacts to the Pathogen’s Environment

The TIR-containing protein C (TcpC) of the uropathogenic Escherichia coli strain CFT073 modulates innate immunity by interfering with the Toll-like receptor and NALP3 inflammasome signaling cascade. During a urinary tract infection the pathogen encounters epithelial and innate immune cells and repli...

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Detalles Bibliográficos
Autores principales: Hemberger, Jacqueline, Ittensohn, Julia, Griffiths, Hannah, Keller, Maren, Costina, Victor, Albrecht, Simone, Miethke, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835471/
https://www.ncbi.nlm.nih.gov/pubmed/35163072
http://dx.doi.org/10.3390/ijms23031148