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The Promoter of the Immune-Modulating Gene TIR-Containing Protein C of the Uropathogenic Escherichia coli Strain CFT073 Reacts to the Pathogen’s Environment
The TIR-containing protein C (TcpC) of the uropathogenic Escherichia coli strain CFT073 modulates innate immunity by interfering with the Toll-like receptor and NALP3 inflammasome signaling cascade. During a urinary tract infection the pathogen encounters epithelial and innate immune cells and repli...
Autores principales: | Hemberger, Jacqueline, Ittensohn, Julia, Griffiths, Hannah, Keller, Maren, Costina, Victor, Albrecht, Simone, Miethke, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835471/ https://www.ncbi.nlm.nih.gov/pubmed/35163072 http://dx.doi.org/10.3390/ijms23031148 |
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