Challenging Approach to the Development of Novel Estrogen Receptor Modulators Based on the Chemical Properties of Guaiazulene

Tamoxifen, a therapeutic agent for breast cancer, has been associated with genetic polymorphisms in the metabolism of N,N-dialkylaminoethyl substituent, which plays an important role in the expression of selective estrogen receptor modulator (SERM) activity. To solve this problem, we developed a nov...

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Detalles Bibliográficos
Autores principales: Ohta, Kiminori, Kaise, Asako, Ogawa, Takumi, Endo, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835499/
https://www.ncbi.nlm.nih.gov/pubmed/35163039
http://dx.doi.org/10.3390/ijms23031113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835499/
https://www.ncbi.nlm.nih.gov/pubmed/35163039
http://dx.doi.org/10.3390/ijms23031113

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