Evidence for Inhibitory Perturbations on the Amplitude, Gating, and Hysteresis of A-Type Potassium Current, Produced by Lacosamide, a Functionalized Amino Acid with Anticonvulsant Properties

Lacosamide (Vimpat(®), LCS) is widely known as a functionalized amino acid with promising anti-convulsant properties; however, adverse events during its use have gradually appeared. Despite its inhibitory effect on voltage-gated Na(+) current (I(Na)), the modifications on varying types of ionic curr...

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Detalles Bibliográficos
Autores principales: Cho, Hsin-Yen, Chuang, Tzu-Hsien, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835568/
https://www.ncbi.nlm.nih.gov/pubmed/35163091
http://dx.doi.org/10.3390/ijms23031171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835568/
https://www.ncbi.nlm.nih.gov/pubmed/35163091
http://dx.doi.org/10.3390/ijms23031171

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