Deep Resequencing of 9 Candidate Genes Identifies a Role for ARAP1 and IGF2BP2 in Modulating Insulin Secretion Adjusted for Insulin Resistance in Obese Southern Europeans

Type 2 diabetes is characterized by impairment in insulin secretion, with an established genetic contribution. We aimed to evaluate common and low-frequency (1–5%) variants in nine genes strongly associated with insulin secretion by targeted sequencing in subjects selected from the extremes of insul...

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Detalles Bibliográficos
Autores principales: Bailetti, Diego, Sentinelli, Federica, Prudente, Sabrina, Cimini, Flavia Agata, Barchetta, Ilaria, Totaro, Maria, Di Costanzo, Alessia, Barbonetti, Arcangelo, Leonetti, Frida, Cavallo, Maria Gisella, Baroni, Marco Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835579/
https://www.ncbi.nlm.nih.gov/pubmed/35163144
http://dx.doi.org/10.3390/ijms23031221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835579/
https://www.ncbi.nlm.nih.gov/pubmed/35163144
http://dx.doi.org/10.3390/ijms23031221

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