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In Vitro Characterization of Sphingosine 1-Phosphate Receptor 1 (S1P(1)) Expression and Mediated Migration of Primary Human T and B Cells in the Context of Cenerimod, a Novel, Selective S1P(1) Receptor Modulator
Cenerimod is a potent, selective sphingosine 1-phosphate receptor 1 (S1P(1)) modulator currently investigated in a Phase IIb study in patients with systemic lupus erythematosus (SLE) (NCT03742037). S1P(1) receptor modulators sequester circulating lymphocytes within lymph nodes, thereby reducing path...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835580/ https://www.ncbi.nlm.nih.gov/pubmed/35163112 http://dx.doi.org/10.3390/ijms23031191 |