In Vitro Characterization of Sphingosine 1-Phosphate Receptor 1 (S1P(1)) Expression and Mediated Migration of Primary Human T and B Cells in the Context of Cenerimod, a Novel, Selective S1P(1) Receptor Modulator

Cenerimod is a potent, selective sphingosine 1-phosphate receptor 1 (S1P(1)) modulator currently investigated in a Phase IIb study in patients with systemic lupus erythematosus (SLE) (NCT03742037). S1P(1) receptor modulators sequester circulating lymphocytes within lymph nodes, thereby reducing path...

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Detalles Bibliográficos
Autores principales: Schlicher, Lisa, Kulig, Paulina, von Münchow, Audrey, Murphy, Mark J., Keller, Marcel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835580/
https://www.ncbi.nlm.nih.gov/pubmed/35163112
http://dx.doi.org/10.3390/ijms23031191

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