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Impairment of Anti-Aggregatory Responses to Nitric Oxide and Prostacyclin: Mechanisms and Clinical Implications in Cardiovascular Disease

The propensity towards platelet-rich thrombus formation increases substantially during normal ageing, and this trend is mediated by decreases in platelet responsiveness to the anti-aggregatory nitric oxide (NO) and prostacyclin (PGI(2)) pathways. The impairment of soluble guanylate cyclase and adeny...

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Detalles Bibliográficos
Autores principales: Chirkov, Yuliy Y., Nguyen, Thanh H., Horowitz, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835624/
https://www.ncbi.nlm.nih.gov/pubmed/35162966
http://dx.doi.org/10.3390/ijms23031042