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Multidimensional Functional Profiling of Human Neuropathogenic FOXG1 Alleles in Primary Cultures of Murine Pallial Precursors

FOXG1 is an ancient transcription factor gene mastering telencephalic development. A number of distinct structural FOXG1 mutations lead to the “FOXG1 syndrome”, a complex and heterogeneous neuropathological entity, for which no cure is presently available. Reconstruction of primary neurodevelopmenta...

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Detalles Bibliográficos
Autores principales: Frisari, Simone, Santo, Manuela, Hosseini, Ali, Manzati, Matteo, Giugliano, Michele, Mallamaci, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835715/
https://www.ncbi.nlm.nih.gov/pubmed/35163265
http://dx.doi.org/10.3390/ijms23031343