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Nischarin Deletion Reduces Oxidative Metabolism and Overall ATP: A Study Using a Novel NISCH(Δ5-6) Knockout Mouse Model

Nischarin (Nisch) is a cytosolic scaffolding protein that harbors tumor-suppressor-like characteristics. Previous studies have shown that Nisch functions as a scaffolding protein and regulates multiple biological activities. In the current study, we prepared a complete Nisch knockout model, for the...

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Detalles Bibliográficos
Autores principales: Nguyen, Tina H., Yousefi, Hassan, Okpechi, Samuel C., Lauterboeck, Lothar, Dong, Shengli, Yang, Qinglin, Alahari, Suresh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835720/
https://www.ncbi.nlm.nih.gov/pubmed/35163298
http://dx.doi.org/10.3390/ijms23031374