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Cryo‐EM structure of the full‐length Lon protease from Thermus thermophilus

In bacteria, Lon is a large hexameric ATP‐dependent protease that targets misfolded and also folded substrates, some of which are involved in cell division and survival of cellular stress. The N‐terminal domain of Lon facilitates substrate recognition, but how the domains confer such activity has re...

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Detalles Bibliográficos
Autores principales: Coscia, Francesca, Löwe, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835725/
https://www.ncbi.nlm.nih.gov/pubmed/34591981
http://dx.doi.org/10.1002/1873-3468.14199